NINJ1

Across TCGA pan-cancer cohorts, NINJ1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NINJ1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NINJ1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NINJ1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where NINJ1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.759	0.366	.001	59	view →
PDAC	DFS	Median	II,III,IV	0.588	0.924	.018	17	view →
CCRCC	OS	Median	III,IV	0.777	1.000	.005	16	view →
LSCC	DFS	Median	III,IV	0.855	0.423	.006	3	view →
HNSC	DFS	Median	II,III,IV	0.892	0.981	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NINJ1–LUAD (DFS)

Open the LUAD breakdown →