NIM1K

Across TCGA patient cohorts, NIM1K protein abundance is significantly associated with the RNA expression of many other genes, with 336 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NIM1K-associated genes across cancer lineages are AQP9, NBN, and PLPPR2. Each is linked with NIM1K in more than 1 cancer types. Because this analysis shows association rather than direction, both NIM1K-to-partner and partner-to-NIM1K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIM1K versus AQP9 in HNSC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIM1K→partner) and Y-score (partner→NIM1K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AQP9 →	+1.617	+2.134	.002	.002	3	1
HNSC	NBN →	+0.449	+1.325	.005	.006	3	1
HNSC	PLPPR2 →	-0.620	-1.965	.009	<.001	3	1
HNSC	TMEM59L →	-0.388	-1.649	.008	.003	3	1
HNSC	DNM1 →	-1.158	-1.924	.002	.005	3	1
HNSC	MAP3K8 →	+0.789	+2.125	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 336 associations by consensus.

NIM1K vs AQP9 — HNSC

Explore this scatter interactively →