NIFKP9

Across TCGA pan-cancer cohorts, NIFKP9 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NIFKP9 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher NIFKP9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NIFKP9 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

LUSC, LUAD, and COAD are the cancer types where NIFKP9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.364	0.668	.003	39	view →
LUAD	DFS	Tertile	All	0.470	0.670	.012	30	view →
COAD	DFS	Tertile	III,IV	0.035	0.698	<.001	27	view →
BLCA	OS	Tertile	III,IV	0.950	0.639	.011	24	view →
SKCM	DFS	Tertile	IV	0.040	0.454	.028	21	view →
LGG	OS	Tertile	All	0.283	0.834	<.001	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	18	view →
TGCT	DFS	Tertile	All	0.177	0.806	.004	18	view →
PCPG	DFS	Tertile	All	0.104	0.903	<.001	18	view →
KIRC	DFS	Tertile	All	0.263	0.633	.030	12	view →
THCA	OS	Tertile	All	0.888	0.986	.037	12	view →
OV	OS	Tertile	III,IV	0.693	0.838	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NIFKP9–LUSC (OS)

Open the LUSC breakdown →