NIFKP7

Across TCGA pan-cancer cohorts, NIFKP7 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated NIFKP7 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher NIFKP7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NIFKP7 expression acts as an unfavorable survival marker, although some lineages such as GBM and SKCM show a favorable association.

KICH, KIRC, and ESCA are the cancer types where NIFKP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.025	0.900	<.001	81	view →
KIRC	DFS	Tertile	All	0.419	0.660	<.001	66	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	30	view →
GBM	DFS	Tertile	All	0.630	0.185	.012	24	view →
SKCM	DFS	Tertile	All	0.911	0.727	.027	21	view →
UCEC	OS	Tertile	All	0.777	0.880	.031	12	view →
BLCA	DFS	Tertile	IV	0.158	0.486	.012	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
HNSC	OS	Tertile	All	0.933	0.675	.036	6	view →
LUAD	OS	Tertile	All	0.164	0.402	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

NIFKP7–KICH (DFS)

Open the KICH breakdown →