NIFKP3

Across TCGA pan-cancer cohorts, NIFKP3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NIFKP3’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NIFKP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NIFKP3 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, HNSC, and BLCA are the cancer types where NIFKP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NIFKP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.204	<.001	7	view →
HNSC	All	All	+0.034	.003	7	view →
BLCA	Female	All	+0.143	.031	4	view →
THCA	Male	All	−0.049	.009	2	view →
COAD	All	All	+0.046	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NIFKP3–LUAD

Open the LUAD breakdown →