Across TCGA cell cohorts, NIF3L1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NIF3L1-associated genes across cancer lineages are IQCF6 and OR12D2. Each is linked with NIF3L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIF3L1-to-partner and partner-to-NIF3L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIF3L1→partner) and Y-score (partner→NIF3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IQCF6 →	+0.311	+4.467	<.001	.004	3	1
LARGE_INTESTINE	OR12D2 →	+0.079	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

NIF3L1 survival (RNA) · tumor vs normal (RNA) · all NIF3L1 data types