NID1

Across TCGA cell cohorts, NID1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,058 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NID1-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Mitochondrial electron transport, cytochrome c to oxygen, and Negative regulation of myoblast fusion. Each is linked with NID1 in more than 10 cancer types. Because this analysis shows association rather than direction, both NID1-to-partner and partner-to-NID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by NID1-low versus NID1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NID1→partner) and Y-score (partner→NID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of telomerase RNA localization to Cajal body →	+0.099	+2.475	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.108	+2.684	<.001	<.001	3	10
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.160	+2.708	<.001	.001	3	10
BONE	Collagen biosynthetic process →	+0.261	+2.883	<.001	<.001	3	10
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+1.952	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of telomere maintenance via telomerase →	+0.071	+2.134	.004	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,058 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by NID1 expression — BREAST

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