NICN1

Across TCGA patient cohorts, NICN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,166 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible NICN1-associated GO terms across cancer lineages are Phosphatidylinositol metabolic process, Obsolete histone methylation, and Glycerophospholipid biosynthetic process. Each is linked with NICN1 in more than 29 cancer types. Because this analysis shows association rather than direction, both NICN1-to-partner and partner-to-NICN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol metabolic process grouped by NICN1-low versus NICN1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NICN1→partner) and Y-score (partner→NICN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Phosphatidylinositol metabolic process →	+0.057	+0.945	<.001	<.001	3	30
SCLC	Obsolete histone methylation →	+0.128	+0.978	<.001	<.001	3	30
SCLC	Glycerophospholipid biosynthetic process →	+0.035	+0.709	<.001	<.001	3	29
SCLC	Obsolete histone H3-K4 methylation →	+0.120	+0.830	<.001	<.001	3	29
SCLC	Phosphatidylinositol biosynthetic process →	+0.053	+0.715	<.001	<.001	3	29
SCLC	Phospholipid biosynthetic process →	+0.061	+1.186	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,166 associations by consensus.

Phosphatidylinositol metabolic process by NICN1 expression — SCLC

Explore this box plot interactively →