NICN1

Across TCGA cell cohorts, NICN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,969 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NICN1-associated GO terms across cancer lineages are Flagellated sperm motility, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, and Methylglyoxal metabolic process. Each is linked with NICN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NICN1-to-partner and partner-to-NICN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by NICN1-low versus NICN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NICN1→partner) and Y-score (partner→NICN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.127	-0.912	<.001	<.001	3	13
OESOPHAGUS	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.044	+0.841	.006	.003	3	13
OESOPHAGUS	Methylglyoxal metabolic process →	+0.191	+1.585	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.127	-0.912	<.001	<.001	3	13
OESOPHAGUS	Cellular detoxification of methylglyoxal →	+0.195	+1.130	<.001	.001	3	12
OESOPHAGUS	Response to methylglyoxal →	+0.195	+1.130	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

Flagellated sperm motility by NICN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →