NIBAN3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NIBAN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,942 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NIBAN3-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Negative regulation of mRNA splicing, via spliceosome, and Negative regulation of RNA splicing. Each is linked with NIBAN3 in more than 11 cancer types. Because this analysis shows association rather than direction, both NIBAN3-to-partner and partner-to-NIBAN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by NIBAN3-low versus NIBAN3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN3→partner) and Y-score (partner→NIBAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHPositive regulation of double-strand break repair →+0.092+0.375.004.008212
LARGE_INTESTINENegative regulation of mRNA splicing, via spliceosome →+0.119+0.237<.001<.001311
BONENegative regulation of RNA splicing →+0.097+0.175<.001.007311
STOMACHPositive regulation of DNA recombination →+0.103+0.427<.001.001311
LUNG_SCLCLate viral transcription →+0.117+0.913<.001.002311
KIDNEYRegulation of myoblast fusion →+0.119+0.290<.001.002311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,942 associations by consensus.

Positive regulation of double-strand break repair by NIBAN3 expression — STOMACH

Box plot of Positive regulation of double-strand break repair in NIBAN3-low vs NIBAN3-high samples in STOMACH.

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Exploration