NIBAN3

Across TCGA cell cohorts, NIBAN3 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NIBAN3-associated genes across cancer lineages are CLDN34, RPE65, and IL22. Each is linked with NIBAN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIBAN3-to-partner and partner-to-NIBAN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLDN34 grouped by NIBAN3-low versus NIBAN3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN3→partner) and Y-score (partner→NIBAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CLDN34 →	+0.030	+3.762	<.001	.007	3	2
BLOOD_Leukemia	RPE65 →	+0.030	+3.153	<.001	.002	3	1
BLOOD_Leukemia	IL22 →	+0.016	+3.762	<.001	.007	3	1
BLOOD_Leukemia	DNASE2B →	+0.042	+3.572	.004	.003	3	1
BLOOD_Leukemia	DSPP →	+0.051	+3.067	.004	.005	3	1
BLOOD_Leukemia	HIGD2B →	+0.044	+3.297	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

CLDN34 by NIBAN3 expression — BLOOD_Leukemia

Explore this box plot interactively →