NIBAN2

Across TCGA patient cohorts, NIBAN2 mutation is significantly associated with the RNA expression of many other genes, with 2,792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NIBAN2-associated genes across cancer lineages are YWHAH, HSPA4L, and CBY1P1. Each is linked with NIBAN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NIBAN2-to-partner and partner-to-NIBAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YWHAH grouped by NIBAN2-low versus NIBAN2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN2→partner) and Y-score (partner→NIBAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	YWHAH →	+0.440	+3.398	.006	.004	3	3
COAD	HSPA4L →	+1.124	+3.362	<.001	.005	3	3
BLCA	CBY1P1 →	+0.261	+5.497	<.001	.004	3	3
LUAD	RNU6-751P →	+0.518	+7.930	<.001	.008	3	3
UCEC	PBK →	+0.796	+2.818	.002	<.001	3	3
UCEC	NIPA1 →	+0.928	+3.480	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,792 associations by consensus.

YWHAH by NIBAN2 expression — SKCM

Explore this box plot interactively →