NIBAN2

Across TCGA cell cohorts, NIBAN2 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NIBAN2-associated genes across cancer lineages are OPN1LW, NPVF, and EDN3. Each is linked with NIBAN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIBAN2-to-partner and partner-to-NIBAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1LW grouped by NIBAN2-low versus NIBAN2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN2→partner) and Y-score (partner→NIBAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OPN1LW →	+0.033	+4.906	<.001	.006	3	1
OESOPHAGUS	NPVF →	+0.020	+4.906	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	EDN3 →	+0.087	+4.209	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	DEFA6 →	+0.056	+4.209	.004	.006	3	1
UPPER_AERODIGESTIVE_TRACT	UTF1 →	+0.170	+4.357	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	CENPVL1 →	+0.040	+4.510	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

OPN1LW by NIBAN2 expression — OESOPHAGUS

Explore this box plot interactively →