NIBAN1

Across TCGA cell cohorts, NIBAN1 mutation is significantly associated with the RNA expression of many other genes, with 355 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NIBAN1-associated genes across cancer lineages are GCAT, KDELR3, and SH3GL2. Each is linked with NIBAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIBAN1-to-partner and partner-to-NIBAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by NIBAN1-low versus NIBAN1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN1→partner) and Y-score (partner→NIBAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.132	+3.364	.005	.002	3	1
LARGE_INTESTINE	KDELR3 →	+1.331	+3.364	<.001	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.222	+3.295	<.001	.006	3	1
LARGE_INTESTINE	NPM3 →	+0.758	+3.364	.001	.002	3	1
LARGE_INTESTINE	USP46 →	+0.722	+3.451	.001	.002	3	1
LARGE_INTESTINE	FMO1 →	+0.083	+2.144	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 355 associations by consensus.

GCAT by NIBAN1 expression — LARGE_INTESTINE

Explore this box plot interactively →