Across TCGA patient cohorts, NHSL2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,268 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NHSL2-associated genes across cancer lineages are PDE1A, CLEC1A, and GEM. Each is linked with NHSL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NHSL2-to-partner and partner-to-NHSL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHSL2→partner) and Y-score (partner→NHSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDE1A →	+0.830	+0.269	<.001	<.001	3	6
CCRCC	CLEC1A →	+0.881	+0.487	<.001	<.001	3	6
LUAD	GEM →	+0.872	+0.340	.002	<.001	3	6
LUAD	HASPIN →	-0.627	-0.292	.005	<.001	3	6
HNSC	MEF2C →	+0.761	+0.255	.002	<.001	3	6
BRCA	CENPI →	-0.992	-0.507	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,268 associations by consensus.

Exploration

NHSL2 survival (RNA) · tumor vs normal (RNA) · all NHSL2 data types