Across TCGA patient cohorts, NHSL2 mutation is significantly associated with the RNA expression of many other genes, with 4,560 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NHSL2-associated genes across cancer lineages are ATP5PBP3, TOMM22P5, and EMID1. Each is linked with NHSL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NHSL2-to-partner and partner-to-NHSL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHSL2→partner) and Y-score (partner→NHSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ATP5PBP3 →	+0.448	+3.847	<.001	.004	3	3
LIHC	TOMM22P5 →	+0.126	+3.856	.001	.008	3	3
UCEC	EMID1 →	-1.122	-3.381	<.001	<.001	3	3
COAD	KSR1 →	-0.776	-3.432	<.001	.005	3	3
UCEC	NFATC4 →	-0.505	-1.536	<.001	.001	3	3
UCEC	DNM1 →	-0.480	-1.533	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

Exploration

NHSL2 survival (RNA) · tumor vs normal (RNA) · all NHSL2 data types