Across TCGA cell cohorts, NHSL2 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NHSL2-associated genes across cancer lineages are Mirin, GSK2801, and Ara-G. Each is linked with NHSL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NHSL2-to-partner and partner-to-NHSL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHSL2→partner) and Y-score (partner→NHSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.414	+2.868	.020	.022	3	1
LARGE_INTESTINE	GSK2801 →	+0.434	+2.871	.003	.021	3	1
LARGE_INTESTINE	Ara-G →	+0.174	+2.944	.029	.018	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.321	+2.871	.015	.021	2	1
LARGE_INTESTINE	BDF00022089a →	+0.300	+2.871	.042	.021	2	1
LARGE_INTESTINE	50869 →	+0.561	+2.900	.004	.015	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

NHSL2 survival (RNA) · tumor vs normal (RNA) · all NHSL2 data types