NHSL1

Across TCGA patient cohorts, NHSL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,827 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NHSL1-associated proteins across cancer lineages are NHSL1_S328, NHSL1_S1386, and VANGL2. Each is linked with NHSL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NHSL1-to-partner and partner-to-NHSL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NHSL1 versus NHSL1_S328 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NHSL1→partner) and Y-score (partner→NHSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NHSL1_S328 →	+0.929	+0.755	<.001	<.001	3	6
BRCA	NHSL1_S1386 →	+0.790	+0.997	<.001	<.001	3	5
HNSC	VANGL2 →	+0.535	+0.457	<.001	.006	3	4
LSCC	PRPF38A →	+0.205	+0.814	<.001	<.001	3	4
BRCA	PSAT1 →	+1.225	+0.638	<.001	<.001	3	4
OV	PSMB10_S230 →	-1.028	-0.927	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,827 associations by consensus.

NHSL1 vs NHSL1_S328 — BRCA

Explore this scatter interactively →