NHP2

Across TCGA pan-cancer cohorts, NHP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NHP2 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NHP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NHP2 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where NHP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.925	.023	18	view →
CCRCC	DFS	Quartile	All	0.707	1.000	.029	4	view →
LUAD	DFS	Median	All	0.814	0.670	.038	4	view →
UCEC	OS	Quartile	All	0.887	1.000	.029	2	view →
LSCC	DFS	Median	All	0.498	0.828	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NHP2–COAD (DFS)

Open the COAD breakdown →