NHLRC4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NHLRC4 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NHLRC4-associated genes across cancer lineages are YAP. Each is linked with NHLRC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NHLRC4-to-partner and partner-to-NHLRC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YAP grouped by NHLRC4-low versus NHLRC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC4→partner) and Y-score (partner→NHLRC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECYAP →+0.220+2.817.016.03631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

YAP by NHLRC4 expression — UCEC

Box plot of YAP in NHLRC4-low vs NHLRC4-high samples in UCEC.

Explore this box plot interactively →

Exploration