NHLRC4

Across TCGA cell cohorts, NHLRC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,951 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NHLRC4-associated GO terms across cancer lineages are Cellular response to lead ion, Negative regulation of myoblast fusion, and Positive regulation of termination of RNA polymerase II transcription. Each is linked with NHLRC4 in more than 5 cancer types. Because this analysis shows association rather than direction, both NHLRC4-to-partner and partner-to-NHLRC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to lead ion grouped by NHLRC4-low versus NHLRC4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC4→partner) and Y-score (partner→NHLRC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular response to lead ion →	+0.099	+0.801	.002	.001	3	6
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.062	+0.489	.004	.002	3	5
BLOOD_Lymphoma	Positive regulation of termination of RNA polymerase II transcription →	+0.064	+0.558	.003	.001	3	5
SOFT_TISSUE	Negative regulation of establishment of protein localization →	+0.043	+0.268	<.001	.004	3	5
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.059	+0.489	.006	.002	3	5
BLOOD_Lymphoma	Positive regulation of termination of DNA-templated transcription →	+0.064	+0.558	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,951 associations by consensus.

Cellular response to lead ion by NHLRC4 expression — BLOOD_Leukemia

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