Across TCGA patient cohorts, NHLRC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,021 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NHLRC3-associated proteins across cancer lineages are ARHGEF7, RPL6, and VPS36. Each is linked with NHLRC3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NHLRC3-to-partner and partner-to-NHLRC3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC3→partner) and Y-score (partner→NHLRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF7 →	+0.185	+0.438	.004	<.001	3	5
BRCA	RPL6 →	-0.408	-0.702	<.001	<.001	3	5
BRCA	VPS36 →	+0.267	+0.684	<.001	<.001	3	5
OV	COG6 →	+0.185	+0.442	.008	.005	3	5
HNSC	TBC1D5 →	+0.259	+0.584	<.001	<.001	3	4
BRCA	TLN2 →	+0.558	+0.640	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,021 associations by consensus.

Exploration

NHLRC3 survival (RNA) · tumor vs normal (RNA) · all NHLRC3 data types