Across TCGA cell cohorts, NHLRC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,769 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NHLRC2-associated GO terms across cancer lineages are Regulation of sister chromatid cohesion, Positive regulation of maintenance of sister chromatid cohesion, and Positive regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with NHLRC2 in more than 15 cancer types. Because this analysis shows association rather than direction, both NHLRC2-to-partner and partner-to-NHLRC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC2→partner) and Y-score (partner→NHLRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of sister chromatid cohesion →	+0.127	+0.593	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of maintenance of sister chromatid cohesion →	+0.135	+0.464	<.001	.003	3	16
SOFT_TISSUE	Positive regulation of maintenance of mitotic sister chromatid cohesion →	+0.135	+0.464	<.001	.003	3	16
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.107	+0.921	<.001	<.001	3	15
URINARY_TRACT	Chromatin looping →	+0.097	+0.641	<.001	<.001	3	15
SOFT_TISSUE	Regulation of maintenance of sister chromatid cohesion →	+0.146	+0.655	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,769 associations by consensus.

Exploration

NHLRC2 survival (RNA) · tumor vs normal (RNA) · all NHLRC2 data types