Across TCGA cell cohorts, NHLRC2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NHLRC2-associated genes across cancer lineages are CNGA3, MMP26, and MOS. Each is linked with NHLRC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NHLRC2-to-partner and partner-to-NHLRC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC2→partner) and Y-score (partner→NHLRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CNGA3 →	+0.036	+4.807	<.001	.006	3	1
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	1
BLOOD_Myeloma	MOS →	+0.040	+4.807	<.001	.006	3	1
LARGE_INTESTINE	GRIN3A →	+0.103	+3.292	.001	.006	3	1
BLOOD_Lymphoma	NEUROG1 →	+0.004	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	OR4N4 →	+0.071	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

NHLRC2 survival (RNA) · tumor vs normal (RNA) · all NHLRC2 data types