Across TCGA patient cohorts, NHLRC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,808 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NHLRC1-associated genes across cancer lineages are KCNE1, LINC01645, and TNS4. Each is linked with NHLRC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NHLRC1-to-partner and partner-to-NHLRC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHLRC1→partner) and Y-score (partner→NHLRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KCNE1 →	+0.555	+0.498	<.001	<.001	3	2
CCRCC	LINC01645 →	+0.564	+0.455	<.001	<.001	3	2
LSCC	TNS4 →	-1.626	-0.439	.005	.003	3	2
LSCC	RPL21P1 →	-0.753	-0.549	<.001	<.001	3	2
BRCA	YWHAZP10 →	-1.784	-1.111	.009	.004	3	2
LSCC	NPM1P29 →	-0.893	-0.483	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,808 associations by consensus.

Exploration

NHLRC1 survival (RNA) · tumor vs normal (RNA) · all NHLRC1 data types