NGFR

Across TCGA pan-cancer cohorts, NGFR RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NGFR’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where NGFR RNA is repressed in tumor relative to normal tissue. In most cancer types NGFR is over-expressed in tumor, although a few such as BLCA and COAD show the opposite, repressed pattern.

BLCA, KIRC, and COAD are the cancer types where NGFR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NGFR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	−2.589	<.001	11	view →
KIRC	Female	All	+1.690	<.001	10	view →
COAD	Male	All	−1.510	<.001	9	view →
LIHC	Male	All	−2.064	<.001	8	view →
BRCA	All	II,III,IV	−2.549	<.001	6	view →
UCEC	All	III,IV	−2.511	<.001	6	view →
READ	All	All	−1.491	.004	4	view →
KIRP	All	All	−0.921	<.001	4	view →
LUSC	Male	All	+1.449	<.001	3	view →
KICH	All	All	+1.176	.007	3	view →
CHOL	Male	All	−1.693	.007	2	view →
PRAD	All	All	−1.034	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NGFR–BLCA

Open the BLCA breakdown →