NGF

Across TCGA pan-cancer cohorts, NGF Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NGF data layer compared with 25 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NGF Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NGF expression acts as an unfavorable survival marker.

LIHC, BLCA, and UCEC are the cancer types where NGF Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.044	0.553	<.001	12	view →
BLCA	OS	Median	IV	0.120	0.599	.021	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ESCA	DFS	Median	II,III,IV	0.149	0.522	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NGF–LIHC (DFS)

Open the LIHC breakdown →