NGF

Across TCGA cell cohorts, NGF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,573 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NGF-associated GO terms across cancer lineages are Pyrimidine-containing compound transmembrane transport, Positive regulation of supramolecular fiber organization, and Wound healing. Each is linked with NGF in more than 12 cancer types. Because this analysis shows association rather than direction, both NGF-to-partner and partner-to-NGF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine-containing compound transmembrane transport grouped by NGF-low versus NGF-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NGF→partner) and Y-score (partner→NGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Pyrimidine-containing compound transmembrane transport →	-0.197	-2.815	.009	.007	3	13
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.098	+2.427	.003	.001	3	12
BONE	Wound healing →	+0.102	+2.219	<.001	<.001	3	12
SOFT_TISSUE	Blood coagulation, fibrin clot formation →	+0.333	+2.088	<.001	<.001	3	12
BREAST	Regulation of fibroblast proliferation →	+0.094	+1.294	<.001	<.001	3	12
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.161	+1.806	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,573 associations by consensus.

Pyrimidine-containing compound transmembrane transport by NGF expression — LIVER

Explore this box plot interactively →