NGEF

Across TCGA cell cohorts, NGEF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,300 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NGEF-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Regulation of myoblast fusion. Each is linked with NGEF in more than 9 cancer types. Because this analysis shows association rather than direction, both NGEF-to-partner and partner-to-NGEF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by NGEF-low versus NGEF-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NGEF→partner) and Y-score (partner→NGEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cilium or flagellum-dependent cell motility →	-0.058	-1.176	<.001	.009	3	10
OVARY	Cilium-dependent cell motility →	-0.058	-1.176	<.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.089	+1.440	<.001	<.001	3	9
OESOPHAGUS	Regulation of intracellular transport →	+0.054	+1.877	.009	.001	3	9
SKIN	Positive regulation of intracellular transport →	+0.061	+1.483	.001	.006	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.089	+1.273	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,300 associations by consensus.

Cilium or flagellum-dependent cell motility by NGEF expression — OVARY

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