NGB

Across TCGA patient cohorts, NGB RNA expression is significantly associated with the protein abundance of many other proteins, with 9,081 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NGB-associated proteins across cancer lineages are CASP10, NPDC1_S229, and FNDC3A. Each is linked with NGB in more than 2 cancer types. Because this analysis shows association rather than direction, both NGB-to-partner and partner-to-NGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NGB versus CASP10 in HNSC, with a Pearson correlation of -0.20.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NGB→partner) and Y-score (partner→NGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CASP10 →	-0.518	-0.627	<.001	.003	3	3
GBM	NPDC1_S229 →	+1.447	+0.808	<.001	<.001	3	3
LSCC	FNDC3A →	-0.336	-0.503	<.001	.003	3	3
LSCC	TRAM1 →	-0.332	-0.581	.001	.001	3	3
GBM	NOS1 →	+0.843	+1.223	<.001	<.001	3	3
LSCC	PPME1 →	+0.240	+0.446	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,081 associations by consensus.

NGB vs CASP10 — HNSC

Explore this scatter interactively →