Across TCGA pan-cancer cohorts, NFYCP2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NFYCP2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where NFYCP2 RNA is repressed in tumor relative to normal tissue. In most cancer types NFYCP2 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, COAD, and LUSC are the cancer types where NFYCP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NFYCP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	−0.053	.012	5	view →
COAD	All	All	+0.121	.004	4	view →
LUSC	Male	II,III,IV	+0.043	.027	2	view →
KICH	Female	II,III,IV	−0.042	.015	2	view →
LIHC	Male	All	+0.008	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: NFYCP2 RNA expression & survival · all NFYCP2 data types