NFYAP1

Across TCGA patient cohorts, NFYAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,474 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NFYAP1-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Regulation of microtubule cytoskeleton organization, and Regulation of DNA-directed DNA polymerase activity. Each is linked with NFYAP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NFYAP1-to-partner and partner-to-NFYAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by NFYAP1-low versus NFYAP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYAP1→partner) and Y-score (partner→NFYAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of chromosome organization →	+0.056	+0.315	<.001	<.001	3	17
STAD	Regulation of microtubule cytoskeleton organization →	+0.056	+0.417	<.001	<.001	3	16
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.066	+0.311	<.001	<.001	3	15
STAD	Positive regulation of mitotic cell cycle phase transition →	+0.052	+0.383	<.001	<.001	3	15
STAD	Regulation of chromatin organization →	+0.049	+0.307	<.001	<.001	3	15
STAD	Regulation of DNA biosynthetic process →	+0.050	+0.345	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,474 associations by consensus.

Positive regulation of chromosome organization by NFYAP1 expression — STAD

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