NFYA

Across TCGA pan-cancer cohorts, NFYA mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NFYA data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NFYA mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NFYA expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, LUAD, and UCEC are the cancer types where NFYA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	1.000	0.897	.044	12	view →
LUAD	OS	Quartile	III,IV	0.660	1.000	.006	6	view →
UCEC	OS	Quartile	All	0.903	1.000	.026	2	view →
PDAC	DFS	Quartile	II,III,IV	0.832	0.620	.032	2	view →
HNSC	DFS	Tertile	III,IV	0.879	0.684	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NFYA–COAD (DFS)

Open the COAD breakdown →