NFYA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NFYA protein abundance is significantly associated with the RNA expression of many other genes, with 8,932 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NFYA-associated genes across cancer lineages are MEFV, FCGR3B, and CEACAM3. Each is linked with NFYA in more than 4 cancer types. Because this analysis shows association rather than direction, both NFYA-to-partner and partner-to-NFYA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFYA versus MEFV in HNSC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYA→partner) and Y-score (partner→NFYA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMEFV →-0.681-0.519.002.00235
HNSCFCGR3B →-1.384-0.655<.001<.00135
LSCCCEACAM3 →-0.534-0.462<.001<.00135
LUADDPP4-DT →-0.920-0.398.008.00134
LSCCABLIM3 →-0.843-0.479<.001.00134
OVSELL →-1.278-0.777.002.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,932 associations by consensus.

NFYA vs MEFV — HNSC

Per-sample scatter of NFYA vs MEFV in HNSC (Pearson r = -0.32).

Explore this scatter interactively →

Exploration