NFYA

Across TCGA patient cohorts, NFYA mutation is significantly associated with the RNA expression of many other genes, with 3,177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NFYA-associated genes across cancer lineages are RNA5SP64, RNA5SP408, and SGO1P1. Each is linked with NFYA in more than 2 cancer types. Because this analysis shows association rather than direction, both NFYA-to-partner and partner-to-NFYA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP64 grouped by NFYA-low versus NFYA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYA→partner) and Y-score (partner→NFYA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP64 →	+0.215	+3.797	<.001	<.001	3	3
UCEC	RNA5SP408 →	+0.279	+2.116	<.001	.008	3	3
CESC	SGO1P1 →	+0.016	+4.837	<.001	.003	3	2
UCEC	RNU6-1180P →	+0.125	+2.938	<.001	.006	3	2
UCEC	AP1B1P1 →	+0.069	+1.676	.001	.004	3	2
UCEC	MLLT10P2 →	+0.153	+2.171	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,177 associations by consensus.

RNA5SP64 by NFYA expression — UCEC

Explore this box plot interactively →