NFYA

Across TCGA cell cohorts, NFYA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,565 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NFYA-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Regulation of transcription initiation by RNA polymerase II, and Regulation of DNA repair. Each is linked with NFYA in more than 14 cancer types. Because this analysis shows association rather than direction, both NFYA-to-partner and partner-to-NFYA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by NFYA-low versus NFYA-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYA→partner) and Y-score (partner→NFYA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of RNA export from nucleus →	+0.126	+0.825	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.080	+0.820	<.001	<.001	3	15
BONE	Regulation of DNA repair →	+0.084	+0.997	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.087	+0.830	<.001	<.001	3	14
LUNG_SCLC	Positive regulation of transcription initiation by RNA polymerase II →	+0.076	+0.806	<.001	<.001	3	14
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.058	+0.706	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,565 associations by consensus.

Negative regulation of RNA export from nucleus by NFYA expression — PANCREAS

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