NFKBIZ

Across TCGA patient cohorts, NFKBIZ protein abundance is significantly associated with the RNA expression of many other genes, with 251 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NFKBIZ-associated genes across cancer lineages are SPOP, SLC4A1AP, and CLEC11A. Each is linked with NFKBIZ in more than 1 cancer types. Because this analysis shows association rather than direction, both NFKBIZ-to-partner and partner-to-NFKBIZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFKBIZ versus SPOP in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIZ→partner) and Y-score (partner→NFKBIZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPOP →	+0.399	+0.949	.004	.007	3	1
OV	SLC4A1AP →	+0.714	+1.258	.003	.008	3	1
BRCA	CLEC11A →	+2.119	+1.019	.009	.007	3	1
BRCA	RUNDC3B →	-0.710	-1.019	<.001	.007	3	1
BRCA	CEP164 →	+0.855	+1.019	.001	.007	3	1
BRCA	RNF130 →	+0.545	+1.019	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

NFKBIZ vs SPOP — OV

Explore this scatter interactively →