NFKBIZ

Across TCGA cell cohorts, NFKBIZ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,756 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NFKBIZ-associated GO terms across cancer lineages are Keratinocyte activation, Lymphocyte apoptotic process, and Leukocyte apoptotic process. Each is linked with NFKBIZ in more than 19 cancer types. Because this analysis shows association rather than direction, both NFKBIZ-to-partner and partner-to-NFKBIZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte activation grouped by NFKBIZ-low versus NFKBIZ-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIZ→partner) and Y-score (partner→NFKBIZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Keratinocyte activation →	+1.809	+2.682	<.001	<.001	3	20
OVARY	Lymphocyte apoptotic process →	+0.157	+2.245	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Leukocyte apoptotic process →	+0.153	+2.125	<.001	.009	3	16
STOMACH	Canonical NF-kappaB signal transduction →	+0.094	+2.072	<.001	.001	3	16
BONE	Keratinocyte proliferation →	+1.698	+2.683	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of T-helper 17 cell differentiation →	+0.137	+1.711	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,756 associations by consensus.

Keratinocyte activation by NFKBIZ expression — SOFT_TISSUE

Explore this box plot interactively →