Across TCGA pan-cancer cohorts, NFKBIL1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NFKBIL1 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NFKBIL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NFKBIL1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where NFKBIL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.907	0.474	<.001	29	view →
LUAD	DFS	Tertile	All	0.718	0.914	.013	19	view →
CCRCC	OS	Tertile	All	1.000	0.326	.020	5	view →
UCEC	DFS	Tertile	All	0.934	0.672	.045	2	view →
GBM	OS	Tertile	All	0.562	0.265	.017	2	view →
PDAC	OS	Median	II,III,IV	0.449	0.725	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: NFKBIL1 tumor-vs-normal RNA expression · all NFKBIL1 data types