NFKBIL1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NFKBIL1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NFKBIL1-associated genes across cancer lineages are Class-switched memory B-cells, mv Endothelial cells, and Endothelial cells. Each is linked with NFKBIL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFKBIL1-to-partner and partner-to-NFKBIL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIL1→partner) and Y-score (partner→NFKBIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECClass-switched memory B-cells →-0.052-3.044.049.01431
UCECmv Endothelial cells →-0.027-3.169.015.01931
UCECEndothelial cells →-0.039-3.313.029.01021
UCEClymphatic Endothelial cells →-0.025-3.281.021.01021
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration