Across TCGA cell cohorts, NFKBIL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NFKBIL1-associated genes across cancer lineages are PRAMEF15, LEUTX, and MBD3L2. Each is linked with NFKBIL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFKBIL1-to-partner and partner-to-NFKBIL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIL1→partner) and Y-score (partner→NFKBIL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRAMEF15 →	+0.352	+4.981	<.001	.008	3	1
CNS	LEUTX →	+0.181	+5.321	<.001	.005	3	1
CNS	MBD3L2 →	+1.117	+4.981	.001	.008	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	WNT8A →	+0.018	+3.632	.007	.003	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

NFKBIL1 survival (RNA) · tumor vs normal (RNA) · all NFKBIL1 data types