NFKBIE

Across TCGA patient cohorts, NFKBIE protein abundance is significantly associated with the RNA expression of many other genes, with 13,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NFKBIE-associated genes across cancer lineages are IL4I1, BIRC3, and TNFRSF9. Each is linked with NFKBIE in more than 6 cancer types. Because this analysis shows association rather than direction, both NFKBIE-to-partner and partner-to-NFKBIE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFKBIE versus IL4I1 in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBIE→partner) and Y-score (partner→NFKBIE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IL4I1 →	+1.336	+0.277	<.001	<.001	3	7
OV	BIRC3 →	+1.044	+0.348	<.001	<.001	3	7
LSCC	TNFRSF9 →	+0.745	+0.348	<.001	<.001	3	7
UCEC	HLA-DQA1 →	+1.067	+0.243	.002	.003	3	7
BRCA	PCED1B-AS1 →	+0.754	+0.254	<.001	.007	3	7
GBM	FCGR2B →	+0.858	+0.149	.001	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,144 associations by consensus.

NFKBIE vs IL4I1 — UCEC

Explore this scatter interactively →