NFKBIA

Across TCGA pan-cancer cohorts, NFKBIA Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NFKBIA data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher NFKBIA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NFKBIA expression acts as an unfavorable survival marker.

MESO, LGG, and HNSC are the cancer types where NFKBIA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.130	0.557	.019	18	view →
LGG	OS	Median	All	0.306	0.811	.007	6	view →
HNSC	OS	Median	All	0.198	0.768	.001	6	view →
LIHC	OS	Median	II,III,IV	0.152	0.614	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NFKBIA–MESO (OS)

Open the MESO breakdown →