NFIX

Across TCGA patient cohorts, NFIX RNA expression is significantly associated with the protein abundance of many other proteins, with 18,413 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NFIX-associated proteins across cancer lineages are NFIX_S361, NFIX_S301, and RPL5. Each is linked with NFIX in more than 5 cancer types. Because this analysis shows association rather than direction, both NFIX-to-partner and partner-to-NFIX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFIX versus NFIX_S361 in LUAD, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NFIX→partner) and Y-score (partner→NFIX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NFIX_S361 →	+0.691	+1.270	<.001	<.001	3	6
LUAD	NFIX_S301 →	+0.853	+1.167	<.001	<.001	3	5
PDAC	RPL5 →	-0.202	-0.610	<.001	<.001	3	5
LSCC	DNAJC1 →	-0.366	-0.546	.003	.002	3	4
GBM	DTX3L_S202 →	-0.411	-0.700	.001	.001	3	4
PDAC	FKBP11 →	-0.756	-0.518	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,413 associations by consensus.

NFIX vs NFIX_S361 — LUAD

Explore this scatter interactively →