NFIL3

Across TCGA cell cohorts, NFIL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,476 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFIL3-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Transforming growth factor beta1 production, and Natural killer cell differentiation. Each is linked with NFIL3 in more than 9 cancer types. Because this analysis shows association rather than direction, both NFIL3-to-partner and partner-to-NFIL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor-mediated signaling pathway grouped by NFIL3-low versus NFIL3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFIL3→partner) and Y-score (partner→NFIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.074	+1.762	<.001	<.001	3	10
BLOOD_Lymphoma	Transforming growth factor beta1 production →	+0.306	+2.207	<.001	<.001	3	10
SKIN	Natural killer cell differentiation →	+0.185	+1.203	<.001	<.001	3	10
CNS	Negative regulation of blood-brain barrier permeability →	+0.347	+1.085	.001	<.001	3	10
BONE	Transforming growth factor beta production →	+0.355	+1.598	<.001	<.001	3	9
SOFT_TISSUE	Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway →	+0.075	+1.130	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,476 associations by consensus.

Regulation of tumor necrosis factor-mediated signaling pathway by NFIL3 expression — BLOOD_Lymphoma

Explore this box plot interactively →