NFIA

Across TCGA cell cohorts, NFIA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,143 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NFIA-associated GO terms across cancer lineages are Regulation of fibrinolysis, Muscle organ development, and Regulation of plasminogen activation. Each is linked with NFIA in more than 9 cancer types. Because this analysis shows association rather than direction, both NFIA-to-partner and partner-to-NFIA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibrinolysis grouped by NFIA-low versus NFIA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFIA→partner) and Y-score (partner→NFIA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of fibrinolysis →	-0.358	-1.271	.001	.003	3	10
URINARY_TRACT	Muscle organ development →	-0.077	-1.128	<.001	<.001	3	8
SOFT_TISSUE	Regulation of plasminogen activation →	-0.239	-1.405	<.001	<.001	3	7
SOFT_TISSUE	Regulation of protein monoubiquitination →	-0.112	-0.888	<.001	<.001	3	7
SOFT_TISSUE	Positive regulation of protein monoubiquitination →	-0.112	-0.888	<.001	<.001	3	7
LARGE_INTESTINE	Regulation of protein localization to cell cortex →	+0.109	+1.135	.003	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,143 associations by consensus.

Regulation of fibrinolysis by NFIA expression — BONE

Explore this box plot interactively →