NFE2L3

Across TCGA patient cohorts, NFE2L3 protein abundance is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. OV shows the largest number of these associations.

The most reproducible NFE2L3-associated genes across cancer lineages are URB2, RUSF1, and SLC25A38. Each is linked with NFE2L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFE2L3-to-partner and partner-to-NFE2L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFE2L3 versus URB2 in OV, with a Pearson correlation of -0.97.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFE2L3→partner) and Y-score (partner→NFE2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	URB2 →	-0.870	-1.384	.001	.003	3	1
OV	RUSF1 →	+0.540	+1.384	.004	.003	3	1
OV	SLC25A38 →	+2.205	+1.384	.002	.003	3	1
OV	NEIL2 →	+1.685	+1.384	.007	.003	3	1
OV	PDE6D →	-1.134	-1.384	.006	.003	3	1
OV	CFAP20DC →	-0.804	-1.384	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

NFE2L3 vs URB2 — OV

Explore this scatter interactively →