NFE2L1

Across TCGA patient cohorts, NFE2L1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,870 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NFE2L1-associated genes across cancer lineages are PHKB, LONP2, and CCDC113. Each is linked with NFE2L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFE2L1-to-partner and partner-to-NFE2L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFE2L1 versus PHKB in BRCA, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFE2L1→partner) and Y-score (partner→NFE2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PHKB →	-0.835	-0.971	<.001	.003	3	1
BRCA	LONP2 →	-1.139	-1.158	<.001	<.001	3	1
BRCA	CCDC113 →	-1.802	-1.317	<.001	.001	3	1
BRCA	RPGRIP1L →	-0.811	-1.438	.005	.002	3	1
BRCA	TTC26 →	-0.840	-1.146	.006	.008	3	1
BRCA	RSPH4A →	-0.580	-0.971	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,870 associations by consensus.

NFE2L1 vs PHKB — BRCA

Explore this scatter interactively →