NFATC3

Across TCGA cell cohorts, NFATC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,578 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NFATC3-associated GO terms across cancer lineages are Nucleocytoplasmic transport, Nuclear transport, and Positive thymic T cell selection. Each is linked with NFATC3 in more than 18 cancer types. Because this analysis shows association rather than direction, both NFATC3-to-partner and partner-to-NFATC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleocytoplasmic transport grouped by NFATC3-low versus NFATC3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFATC3→partner) and Y-score (partner→NFATC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.088	+1.288	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.088	+1.277	<.001	<.001	3	19
LIVER	Positive thymic T cell selection →	+1.619	+1.093	<.001	.001	2	19
BONE	Nucleic acid transport →	+0.103	+1.003	<.001	<.001	3	18
BONE	RNA transport →	+0.103	+1.003	<.001	<.001	3	18
BONE	mRNA transport →	+0.144	+1.143	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,578 associations by consensus.

Nucleocytoplasmic transport by NFATC3 expression — UPPER_AERODIGESTIVE_TRACT

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