NFAT5

Across TCGA pan-cancer cohorts, NFAT5 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NFAT5 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NFAT5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NFAT5 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PDAC and HNSC are the cancer types where NFAT5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.249	0.494	.003	22	view →
HNSC	DFS	Tertile	II,III,IV	0.976	0.905	.026	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NFAT5–PDAC (OS)

Open the PDAC breakdown →